Genes, microbes, and T cells--new therapeutic targets in Crohn's disease

N Engl J Med. 2002 Feb 21;346(8):614-6. doi: 10.1056/NEJM200202213460812.
No abstract available

Publication types

  • Review

MeSH terms

  • Apoptosis
  • Carrier Proteins*
  • Crohn Disease / genetics*
  • Crohn Disease / immunology
  • Genetic Predisposition to Disease
  • Humans
  • Intracellular Signaling Peptides and Proteins*
  • NF-kappa B / metabolism
  • Nod2 Signaling Adaptor Protein
  • Proteins / genetics*
  • Receptors, Cell Surface / metabolism
  • Signal Transduction
  • Tumor Necrosis Factor-alpha / physiology

Substances

  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • NF-kappa B
  • NOD2 protein, human
  • Nod2 Signaling Adaptor Protein
  • Proteins
  • Receptors, Cell Surface
  • Tumor Necrosis Factor-alpha