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J Pharm Sci. 1975 Sep;64(9):1547-9.

Spectrophotometric determination of acetaminophen and dichloralantipyrine in capsules.

Abstract

A rapid method for the routine determination of acetaminophen and dichloralantipyrine in capsules is reported. The determination of acetaminophen is based on the ability of its hydrolytic product, p-aminophenol, to produce an intensive yellow color with vanillin. The determination of dichloralantipyrine is based on the fact that it, as well as its major metabolite chloral hydrate, produces a blue color with quinaldine ethiodide. No interferences were encountered, and good recovery and precision data were obtained.

PMID:
1185577
[Indexed for MEDLINE]

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