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Trends Neurosci. 2002 Mar;25(3):124-6.

Rhodopsin phosphorylation: from terminating single photon responses to photoreceptor dark adaptation.

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1
Dept of Ophthalmology, Harvard Medical School and the Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA. vadim_arshavsky@meei.harvard.edu

Abstract

Rhodopsin phosphorylation has provided one of the first examples of the ubiquitous regulatory pattern of specific kinases downregulating the activity of G-protein-coupled receptors. However, only recently have studies in living animals allowed us to consider the role of rhodopsin phosphorylation in a broader spectrum of visual functions, ranging from the ability of rods to generate reproducible electrical responses to their ability to adapt to darkness after substantial light exposures.

PMID:
11852136
[Indexed for MEDLINE]
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