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Curr Opin Biotechnol. 2001 Dec;12(6):607-12.

Advances in proteome analysis by mass spectrometry.

Author information

1
Institute for Systems Biology, 4225 Roosevelt Way NE, Suite 200, Seattle, WA 98105, USA. tgriffin@systemsbiology.org

Abstract

Proteome characterization using mass spectrometry is essential for the systematic investigation of biological systems and for the study of gene function. Recent advances in this multifaceted field have occurred in four general areas: protein and peptide separation methodologies; selective labeling chemistries for quantitative measurement of peptide and protein abundances; characterization of post-translational protein modifications; and instrumentation.

PMID:
11849943
DOI:
10.1016/s0958-1669(01)00268-3
[Indexed for MEDLINE]

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