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Bioinformatics. 2002 Feb;18(2):337-8.

Generating samples under a Wright-Fisher neutral model of genetic variation.

Author information

1
Department of Ecology and Evolution, University of Chicago, 1101 E. 57th Street, Chicago, IL 60637, USA. rr-hudson@uchicago.edu

Abstract

A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright-Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.

PMID:
11847089
DOI:
10.1093/bioinformatics/18.2.337
[Indexed for MEDLINE]

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