Format

Send to

Choose Destination
See comment in PubMed Commons below
Bipolar Disord. 2001 Dec;3(6):270-5.

Psychiatric diagnoses in the context of genetic studies of bipolar disorder.

Author information

  • 1Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.

Abstract

Precise definition of the phenotype is an issue of critical importance for the future success of genetic studies of bipolar disorders. So far, an uncertain phenotypic spectrum and genetic heterogeneity are realities that have hampered progress in genetic studies. While recognition of a broader spectrum of related illnesses is important for some applications, for genetic studies a narrow spectrum of illness closely tied to the genotype is paramount. This paper highlights current dilemmas and trends associated with phenotype specification and traces historical approaches. Finally, we explore a number of strategic directions in the diagnostic approach to bipolar disorders that may better serve genetic studies.

PMID:
11843777
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center