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Lipids. 2001;36 Suppl:S91-7.

The effect of n-3 fatty acids on low density lipoprotein subfractions.

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Centre for Nutrition & Food Safety, School of Biomedical & Life Sciences, University of Surrey, Guildford,United Kingdom.


A predominance of small, dense low density lipoprotein (LDL) represents a significant source of increased risk for the development of coronary heart disease in Westernized countries. Dietary long-chain n-3 polyunsaturated fatty acids exert a potent triglyceride-lowering effect that redistributes LDL subfractions toward larger and lighter particles. These dietary fatty acids thus have a key role to play in providing protection against this particularly atherogenic type of LDL.

[Indexed for MEDLINE]

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