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Ann Intern Med. 2002 Feb 5;136(3):181-91.

Alcohol consumption and risk for congestive heart failure in the Framingham Heart Study.

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1
National Heart, Lung, and Blood Institute's Framingham Heart Study, National Institutes of Health, Framingham, Massachusetts 01702, USA.

Abstract

BACKGROUND:

Although excessive alcohol consumption can promote cardiomyopathy, little is known about the association between alcohol consumption and risk for congestive heart failure in the community.

OBJECTIVE:

To determine the relation between alcohol consumption and risk for congestive heart failure in the community.

DESIGN:

Community-based, prospective observational study.

SETTING:

Framingham, Massachusetts.

PARTICIPANTS:

Participants in the Framingham Heart Study who were free of congestive heart failure and coronary heart disease.

MEASUREMENTS:

Self-reported alcohol consumption; sex-specific rates of congestive heart failure per 1000 person-years of follow-up by level of alcohol consumption.

RESULTS:

In men, 99 cases of congestive heart failure occurred during 26 035 person-years of follow-up. In women, 120 cases of congestive heart failure occurred during 35 563 person-years of follow-up. After adjustment for multiple confounders, risk for congestive heart failure was lower among men at all levels of alcohol consumption compared with men who consumed less than 1 drink/wk. The hazard ratio for congestive heart failure was lowest among men who consumed 8 to 14 drinks/wk (0.41 [95% CI, 0.21 to 0.81]) compared with those who consumed less than 1 drink/wk. In women, the age-adjusted hazard ratio for congestive heart failure was lowest among those who consumed 3 to 7 drinks/wk (0.49 [CI, 0.25 to 0.96]) compared with those who consumed less than 1 drink/wk. However, after adjustment for multiple predictors of congestive heart failure, this association was no longer statistically significant.

CONCLUSIONS:

In the community, alcohol consumption is not associated with increased risk for congestive heart failure, even among heavy drinkers (> or = 15 drinks/wk in men and > or = 8 drinks/wk in women). To the contrary, when consumed in moderation, alcohol appears to protect against congestive heart failure.

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PMID:
11827493
[Indexed for MEDLINE]

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