Format

Send to

Choose Destination
Swiss Med Wkly. 2001 Oct 20;131(41-42):595-602.

Procalcitonin: how a hormone became a marker and mediator of sepsis.

Author information

1
Division of Endocrinology, Diabetology and Clinical Nutrition, Department of Internal Medicine, University Hospitals, Basel, Switzerland. happymiller@bigfoot.com

Abstract

Calcitonin was discovered in the early 1960s [1], at which time it was assumed to be a single hormone with a yet-to-be-determined role in human physiology. Since then it has been found to be only one entity among a large array of related circulating peptides, at least one of which has a pivotal role in the host response to microbial infections [2, 3]. The aim of this review is to describe this metamorphosis of an endocrine hormone to a new class of hormokine mediators in infectious diseases.

PMID:
11820070
DOI:
2001/41/smw-09751
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center