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Clin Perinatol. 2001 Dec;28(4):721-34.

Etiology and epidemiology of preterm premature rupture of the membranes.

Author information

1
Department of Obstetrics and Gynecology, Brown University, Women and Infants Hospital, Providence, Rhode Island, USA.

Abstract

Preterm premature rupture of membranes continues to be a common complication of pregnancy with significant implications for perinatal outcome. Unfortunately, given the multiple risk factors that have been presented, which are reportedly associated with PPROM, attempts to reduce the incidence of this clinical event may seem daunting to the clinician. Despite this, one should attempt to address the potential risk factors that avail themselves to change. Unfortunately, although many risk factors have been identified, there are few randomized intervention trials for PPROM prevention. Examples of interventions documented to be beneficial include smoking cessation and screening for and treatment of chlamydial infections. These seem to be reasonable and logical interventions to consider in general, and may potentially have an effect on various causal agents of PPROM.

PMID:
11817185
DOI:
10.1016/s0095-5108(03)00073-3
[Indexed for MEDLINE]

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