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J Pediatr. 2002 Jan;140(1):125-7.

Thalidomide therapy for recalcitrant systemic onset juvenile rheumatoid arthritis.

Author information

1
Division of Pediatric Rheumatology, Hospital for Special Surgery, Department of Pediatrics, Sanford Weill Medical Center of Cornell University, New York 10021, USA.

Abstract

Systemic onset juvenile rheumatoid arthritis unresponsive to nonsteroidal anti-inflammatory drugs may be controlled with corticosteroids, but these drugs have significant side effects. We report 2 steroid-dependent children with systemic onset juvenile rheumatoid arthritis who did not respond to multiple nonsteroidal anti-inflammatory drugs, methotrexate, azathioprine, cyclosporine, and etanercept. Both children had significant improvement with thalidomide therapy.

PMID:
11815776
DOI:
10.1067/mpd.2002.120835
[Indexed for MEDLINE]

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