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Trends Neurosci. 2002 Feb;25(2):64-7.

Molecular morphogens for dendritic spines.

Author information

  • 1Dept of Neurobiology, Duke University Medical Center, Box 3209, Durham, NC 27710, USA. ehlers@neuro.duke.edu

Abstract

Three protein components of the postsynaptic density--Shank, Homer and SPAR--have been found to regulate the structural and molecular organization of dendritic spines. These new studies reveal linkages between receptor complexes, the actin cytoskeleton and signaling molecules that help shape spines.

PMID:
11814549
[PubMed - indexed for MEDLINE]

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