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Arch Virol. 2001 Dec;146(12):2263-74.

Structural dynamics, an intrinsic property of viral capsids.

Author information

1
Institut de Biologie Mol├ęculaire et Cellulaire du CNRS, Strasbourg, France.

Abstract

In this review, we emphasize that high-resolution models of the structures of small plant and animal viruses obtained by X-ray crystallography are static and insufficient to describe the behavior of these virions. Viral capsids are highly flexible and may undergo conformational changes under physiological conditions without collapse of the virions. This flexibility plays a key role in the process of infection.

PMID:
11811678
DOI:
10.1007/s007050170001
[Indexed for MEDLINE]

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