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Nature. 2002 Jan 10;415(6868):227-33.

The failing heart.

Author information

1
Department of Pediatrics (Cardiology), Baylor College of Medicine, Houston, Texas 77030, USA. jtowbin@bcm.tmc.edu

Abstract

Cardiomyopathies are disorders affecting heart muscle that usually result in inadequate pumping of the heart. They are the most common cause of heart failure and each year kill more than 10,000 people in the United States. In recent years, there have been breakthroughs in understanding the molecular mechanisms involved in this group of conditions, with knowledge of the genetic basis for cardiomyopathies perhaps seeing the largest advance, enabling clinicians to devise improved diagnostic strategies and preparing the stage for new therapies.

PMID:
11805847
DOI:
10.1038/415227a
[Indexed for MEDLINE]

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