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Neuroimage. 2002 Feb;15(2):386-95.

Detection of neural activity in fMRI using maximum correlation modeling.

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  • 1Department of Biomedical Engineering, Link√∂ping University, Link√∂ping, Sweden.

Abstract

A technique for detecting neural activity in functional MRI data is introduced. It is based on a novel framework termed maximum correlation modeling. The method employs a spatial filtering approach that adapts to the local activity patterns, which results in an improved detection sensitivity combined with good specificity. A spatially varying hemodynamic response is simultaneously modelled by a sum of two gamma functions. Comparisons to traditional analysis methods are made using both synthetic and real data. The results indicate that the maximum correlation modeling approach is a strong alternative for analyzing fMRI data.

PMID:
11798273
DOI:
10.1006/nimg.2001.0972
[PubMed - indexed for MEDLINE]
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