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J Pediatr Endocrinol Metab. 2001 Nov-Dec;14(9):1635-9.

Serum concentration of free T3, free T4 and TSH in healthy children.

Author information

1
Institute of General Pathology and Oncology, Faculty of Medicine, Second University of Naples, Italy. rialab@usa.net

Abstract

OBJECTIVE:

It is rare that manufacturers report age-related FT3, FT4 and TSH normal ranges in healthy children.

STUDY DESIGN:

Using a solid phase time-resolved fluoroimmunometric method, we determined serum FT3, FT4 and TSH in 3,360 healthy children, age 2-16 years, that we grouped into two age ranges (2-7 yr and 9-16 yr).

RESULTS:

Boys' and girls' mean serum thyroid hormone values substantially overlap in all age groups. In the age range 2-7 yr, FT3, FT4 and TSH values were 0.10-0.67 ng/dl (mean 0.37 ng/dl), range 0.45-2.29 ng/dl (mean 1.18 ng/dl) and 0.10-5.9 microU/ml (mean 2.2 microU/ml), respectively. In the age range 9-16 yr, FT3, FT4 and TSH values were 0.11-0.53 ng/dl (mean 0.35 ng/dl), 0.69-1.69 ng/dl (mean 1.07 ng/dl) and 0.20-6.1 microU/ml (mean 2.3 pU/ml), respectively.

CONCLUSION:

Our results represent a useful set of reference values in children and can help physicians in the management of thyroid diseases.

PMID:
11795654
[Indexed for MEDLINE]

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