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[Effect of yangxue antai granule in preventing and treating habitual abortion and its effect on short life T-suppressor cell].

[Article in Chinese]

Author information

1
Beijing Hospital of Gynaecology and Obstetrics, Beijing (100006).

Abstract

OBJECTIVE:

To study the influence of T-suppressor cell (Ts cell) on habitual abortion (HA) and to observe the regulatory effect of Yangxue Antai Granule (YXATG) on Ts cell and its effect on fetus preservation.

METHODS:

Ts cell activity of 56 pregnant women with HA history was tested with method of shot life Ts cell activity (MTT method) during early pregnancy, and were followed up in middle and late pregnancy in 20 cases of them. All the 56 patients received YXATG treatment. Groups of normal early pregnant, normal non-pregnant and non-pregnant women but with history of habitual abortion were involved in this study as control.

RESULTS:

Ts cell activity in early pregnancy was lower than that of middle and late pregnancy (P < 0.01, P < 0.001), and also lower than that of the control groups (P < 0.01, P < 0.001). The successful rate of fetus preservation of YXATG was 98.2%, and 98.0% of the cases got a normal delivery.

CONCLUSION:

Low Ts cell activity might be the immunologic etiology of HA. The fetus preservative effect of YXATG might be due to its regulatory effect on Ts cell.

PMID:
11789258
[Indexed for MEDLINE]

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