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J Neurol Neurosurg Psychiatry. 2002 Jan;72(1):12-21.

Neuropsychiatry of the basal ganglia.

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Academic Department of Psychiatry, St Bartholomew's and the Royal London School of Medicine, Whitechapel Road, London E1 1BB, UK.


This review aims to relate recent findings describing the role and neural connectivity of the basal ganglia to the clinical neuropsychiatry of basal ganglia movement disorders and to the role of basal ganglia disturbances in "psychiatric"' states. Articles relating to the relevant topics were initially collected through MEDLINE and papers relating to the clinical conditions discussed were also reviewed. The anatomy and connections of the basal ganglia indicate that these structures are important links between parts of the brain that have classically been considered to be related to emotional functioning and brain regions previously considered to have largely motor functions. The basal ganglia have a role in the development and integration of psychomotor behaviours, involving motor functions, memory and attentional mechanisms, and reward processes.

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Free PMC Article

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