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[Influence of flavonoid of Astragalus membranaceus's stem and leaves on the function of cell mediated immunity in mice].

[Article in Chinese]

Author information

1
Heilongjiang University of TCM, Harbin (150040).

Abstract

OBJECTIVE:

To investigate the immune regulation of flavonoid of Astragalus membranaceus's stem and leaves (FAM).

METHODS:

Changes of total T cell count and subsets in mice were determined by monoclonal antibody assay before and after treatment with FAM, and the LAK activity was tested simultaneously by isotope technique.

RESULTS:

FAM could promote the proliferation of lymphocytes induced by ConA, raise the T cell count and regulate the T cell subsets disorder, elevate the LAK activity induced by IL-2.

CONCLUSION:

FAM possesses the effect of immune stimulation and immune regulation in treating immunosuppressive mice. This study provides the experimental basis for clinical application of FAM.

PMID:
11783202
[Indexed for MEDLINE]

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