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Trends Biotechnol. 2001 Oct;19(10 Suppl):S23-7.

Exploring the protein interactome using comprehensive two-hybrid projects.

Author information

1
Division of Genome Biology, Cancer Research Institute, Kanazawa University, Japan. titolab@kenkroku.kanazawa-u.ac.jp

Abstract

Large-scale two-hybrid projects were used in an approach to examine protein-protein interactions. Despite the various limitations of this approach, these projects revealed a wealth of novel interactions, and the protein interactome may be much larger than expected.

PMID:
11780966
DOI:
10.1016/S0167-7799(01)01790-5
[Indexed for MEDLINE]

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