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Cell. 2001 Dec 28;107(7):815-8.

Why is p53 acetylated?

Author information

1
Department of Biological Sciences, Columbia University, New York, NY 10027, USA. clp@columbia.edu

Abstract

Recent studies suggest that acetylation of the p53 tumor suppressor protein is not important for its DNA binding activity, as was previously thought. We discuss here a number of theories as to how this modification may serve to regulate the protein's functions.

PMID:
11779456
DOI:
10.1016/s0092-8674(01)00619-5
[Indexed for MEDLINE]
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