Format

Send to

Choose Destination
Zhonghua Jie He He Hu Xi Za Zhi. 2000 Aug;23(8):478-9.

[Dendritic cell infiltration in lung adenocarcinoma and its effect on prognosis].

[Article in Chinese]

Author information

1
Department of Pathology, Cancer Hospital of Hubei Province, Wuhan 430070, China.

Abstract

OBJECTIVE:

To study the infiltration degree of dendritic cells in lung adenocarcinoma and its effect on prognosis.

METHODS:

S-100 protein was used as the specific marker for dendritic cells, and immunohistochemistry was employed to detect the distribution of dendritic cells in lung adenocarcinoma.

RESULTS:

Among 46 cases of lung adenocarcinoma, 19 were markedly infiltrated by dendritic cells, the five-year survival rate being 61%; 27 showed slight infiltration, the five-year survival rate being 21%. Among the 46 cases of adenocarcinoma, 26 were low differentiated adenocarcinoma, in which 10 were infiltrated markedly by dendritic cells, five-year survival rate being 57%; and 16 were slightly infiltrated, five-year survival rate being 16%. These data were evaluated with the log-rank test, which showed a significant difference between the markedly infiltrated group and the slightly infiltrated group.

CONCLUSION:

The prognosis of lung adenocarcinoma which markedly infiltrated by dendritic cells is better than that of slightly infiltrated by dendritic cells.

PMID:
11778262
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center