Send to

Choose Destination
Zhonghua Jie He He Hu Xi Za Zhi. 2000 Aug;23(8):478-9.

[Dendritic cell infiltration in lung adenocarcinoma and its effect on prognosis].

[Article in Chinese]

Author information

Department of Pathology, Cancer Hospital of Hubei Province, Wuhan 430070, China.



To study the infiltration degree of dendritic cells in lung adenocarcinoma and its effect on prognosis.


S-100 protein was used as the specific marker for dendritic cells, and immunohistochemistry was employed to detect the distribution of dendritic cells in lung adenocarcinoma.


Among 46 cases of lung adenocarcinoma, 19 were markedly infiltrated by dendritic cells, the five-year survival rate being 61%; 27 showed slight infiltration, the five-year survival rate being 21%. Among the 46 cases of adenocarcinoma, 26 were low differentiated adenocarcinoma, in which 10 were infiltrated markedly by dendritic cells, five-year survival rate being 57%; and 16 were slightly infiltrated, five-year survival rate being 16%. These data were evaluated with the log-rank test, which showed a significant difference between the markedly infiltrated group and the slightly infiltrated group.


The prognosis of lung adenocarcinoma which markedly infiltrated by dendritic cells is better than that of slightly infiltrated by dendritic cells.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center