Ecstasy is a recreational drug that is increasing in popularity, particularly in young adolescents. Its appeal involves its euphoric effects and a feeling of empathy for others (hence the nickname "hug drug"). This appeal may be furthered by a misleading and anecdotal perception of safety. Cases of adverse effects, toxic reactions, and fatalities are increasingly being reported in the medical literature, as well as in the popular press. Adverse effects include hyperthermia, seizures, cardiac abnormalities, and hyponatremia. Long-term Ecstasy use may result in serotonin terminal degeneration and depletion, which may result in psychiatric and cognitive sequelae. Controversy surrounds the legalization of Ecstasy for medicinal purposes.