Format

Send to

Choose Destination
Biosci Biotechnol Biochem. 2001 Oct;65(10):2306-10.

Antibacterial agents that inhibit histidine protein kinase YycG of Bacillus subtilis.

Author information

1
Department of Agricultural Chemistry, Kinki University, Nara, Japan.

Abstract

We demonstrated in vitro that YycG-YycF of Bacillus subtilis constitutes a two-component system and shows a specificity of the sensor protein for the cognate phosphorylation partner. Based on inhibition of such an autophosphorylation of YycG, we searched imidazole and zerumbone derivatives to identify the antibacterial agents such as NH125, NH126, NH127, and NH0891.

PMID:
11758928
DOI:
10.1271/bbb.65.2306
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Taylor & Francis Icon for J-STAGE, Japan Science and Technology Information Aggregator, Electronic
Loading ...
Support Center