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Bioorg Med Chem Lett. 2002 Jan 21;12(2):255-9.

Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase.

Author information

1
Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London WC1H OAJ, UK. c.m.marson@ucl.ac.uk

Abstract

Cyclic acid anhydrides possessing a lipid chain have been shown to be a new class of non-peptidic inhibitors of geranylgeranyl protein-transferase type I (GGPTase-I).

PMID:
11755366
DOI:
10.1016/s0960-894x(01)00718-1
[Indexed for MEDLINE]

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