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Bioorg Med Chem Lett. 2002 Jan 21;12(2):141-5.

Synthesis and structure-activity relationships of oxime neurokinin antagonists: discovery of potent arylamides.

Author information

1
Schering-Plough Research Institute, 2015 Galloping Hill Rd, Kenilworth, NJ 07033-1300, USA. neng-yang.shih@spcorp.com

Abstract

The structural modification of the benzylic ether region of oxime 1 has resulted in the identification of several novel aryl amides as selective or dual NK(1)/NK(2) antagonists.

PMID:
11755340
DOI:
10.1016/s0960-894x(01)00709-0
[Indexed for MEDLINE]

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