Three new dihydroisocoumarins from the Greek endemic species Scorzonera cretica

J Nat Prod. 2001 Dec;64(12):1585-7. doi: 10.1021/np0103665.

Abstract

Extracts of the Greek endemic species Scorzonera cretica afforded three new compounds, the dihydroisocoumarin scorzocreticin (1) and its glycosides, scorzocreticoside I (2) and scorzocreticoside II (3), as well as 11 known compounds. The structures of the isolated compounds were elucidated on the basis of spectral data and chemical methods. The absolute configurations of 1-3 were established using circular dichroism.

MeSH terms

  • Asteraceae / chemistry*
  • Chromatography
  • Circular Dichroism
  • Coumarins / chemistry
  • Coumarins / isolation & purification*
  • Coumarins / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Greece
  • Hydrolysis
  • Isocoumarins
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Ochratoxins / chemistry
  • Spectrophotometry, Ultraviolet

Substances

  • Coumarins
  • Glycosides
  • Isocoumarins
  • Ochratoxins
  • scorzocreticin
  • scorzocreticoside I
  • scorzocreticoside II
  • ochracin