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HIV Med. 2001 Jan;2(1):59-60.

L-Carnitine in the treatment of HIV-associated lipodystrophy syndrome.

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Specialized practice for HIV and Hepatogastroenterology, Duesseldorf, Germany.


The objective of this pilot study was to assess the effect of L-carnitine on the course of the HIV-associated lipodystrophy syndrome. Twelve patients presenting with combined atrophic and hypertrophic changes of body fat were treated with L-carnitine 1000 mg bid for 3 months. No marked improvement of the body changes was observed. However a reduction in serum cholesterol levels, but not triglycerides, was noted. These preliminary data do not support the use of L-carnitine for the rapid reversal of advanced fat tissue alterations due to HIV-associated lipodystrophy.

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