Topical mupirocin for eradication of MRSA colonization with mupirocin-resistant strains

M Semret; M A Miller

doi:10.1086/501956

Topical mupirocin for eradication of MRSA colonization with mupirocin-resistant strains

Infect Control Hosp Epidemiol. 2001 Sep;22(9):578-80. doi: 10.1086/501956.

Authors

M Semret¹, M A Miller

Affiliation

¹ Department of Microbiology, SMBD-Jewish General Hospital, Montreal, Quebec, Canada.

PMID: 11732789
DOI: 10.1086/501956

Abstract

Topical mupirocin was able to interrupt colonization of 52% and 68% of methicillin-resistant Staphylococcus aureus (MRSA)-colonized patients carrying mupirocin-resistant and -sensitive strains, respectively, including 44.4% and 85.7% of those colonized only in the nares. Although a trend to decreased effectiveness was seen for clearing mupirocin-resistant MRSA, this agent can decolonize many patients with resistant strains.

MeSH terms

Administration, Topical
Anti-Bacterial Agents / administration & dosage*
Anti-Bacterial Agents / pharmacology
Hospitals, Community
Humans
Infection Control / methods
Methicillin Resistance*
Microbial Sensitivity Tests
Mupirocin / administration & dosage*
Mupirocin / pharmacology
Quebec
Staphylococcal Infections / drug therapy*
Staphylococcus aureus / drug effects*
Staphylococcus aureus / growth & development
Staphylococcus aureus / isolation & purification

Substances

Anti-Bacterial Agents
Mupirocin