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Planta Med. 2001 Nov;67(8):757-60.

Hypotensive effect of chemical constituents from Aloe barbadensis.

Author information

1
Dr. H.M.I. Institute of Pharmacology and Herbal Sciences, Hamdard University, Karachi, Pakistan. rs127pk@yahoo.com

Abstract

Hypotensive effects of aloeemodin, aloin A, elgonica dimer A and bisbenzopyran from Aloe barbadensis have been studied. Aloeemodin has emerged as a potent hypotensive agent in current pharmacological investigations and caused 26 %, 52 %, and 79 % falls in mean arterial blood pressure at the corresponding doses of 0.5, 1, and 3 mg/kg in rats. The paper also describes the absolute configuration of elgonica dimer A (1).

PMID:
11731923
DOI:
10.1055/s-2001-18348
[Indexed for MEDLINE]

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