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Fitoterapia. 2001 Dec;72(8):922-6.

Anxiolytic activity of aerial and underground parts of Passiflora incarnata.

Author information

1
Pharmacognosy Division, University Institute of Pharmaceutical Sciences Panjab University, Chandigarh 160014, India. kdd@glide.net.in

Abstract

The petroleum ether, chloroform, methanol, and water extracts of Passiflora incarnata whole plant and sorted out plant parts have been evaluated for their anxiolytic activity using the elevated plus-maze model in mice. The methanol extracts of leaves, stems, flowers, and whole plant exhibited anxiolytic effects at 100, 125, 200 and 300 mg/kg, respectively. The roots were practically devoid of anxiolytic effects. These results show that roots and flowers of P. incarnata act as natural adulterants by causing a significant increase in the anxiolytic dose. Therefore, separation of these parts is recommended prior to any pharmacological, phytochemical and standardization studies on P. incarnata.

PMID:
11731118
[Indexed for MEDLINE]

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