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J Emerg Med. 2001 Nov;21(4):423-9.

Emergency department D-dimer testing.

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Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.


Since the early 1980s, much attention has been paid to the development of a biochemical marker for venous thromboembolism. D-dimers are derivatives of fibrinolysis and recently have been touted as a means of screening for thromboemoblism. We review the physiologic, pathologic, and chemical bases for this new test, and outline the specific D-dimer assays currently available. We conclude with a discussion of the clinical utility of D-dimer in the evaluation of patients with venous thromboembolism.

[Indexed for MEDLINE]

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