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Neurology. 2001 Nov 27;57(10):1885-8.

Onset of multiple sclerosis associated with anti-TNF therapy.

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1
Division of Brain Mapping, UCLA School of Medicine, Los Angeles, CA, USA. nsicotte@ucla.edu

Abstract

Therapies aimed at inhibiting tumor necrosis factor (TNF), a proinflammatory cytokine implicated in autoimmune disease are effective, especially for rheumatoid arthritis. We report a patient with new onset MS closely associated with the initiation of anti-TNF therapy for juvenile rheumatoid arthritis. It is possible that the inhibition of TNF triggered MS in this individual.

PMID:
11723281
[Indexed for MEDLINE]
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