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Chin Med J (Engl). 1999 Dec;112(12):1125-8.

An ultrasound scoring system for the diagnosis of liver fibrosis and cirrhosis.

Author information

1
Department of Gastroenterology, Beijing Hospital, Beijing 100730, China.

Abstract

OBJECTIVE:

To establish noninvasive semiquantitative ultrasonic criteria for evaluating liver fibrosis and differentiating cirrhosis from chronic hepatitis.

METHODS:

A total of 66 HBsAg positive patients (chronic hepatitis 42 patients, cirrhosis 24) were included. Ultrasonography was performed 24 hours before liver biopsy. A fibrotic scoring system was used to evaluate the ultrasound findings in contrast with fibrotic stages in each patient.

RESULTS:

The total liver fibrotic scores had a significantly positive correlation with the histological liver fibrotic stage (r = 0.952, P < 0.001); the stage of histological liver fibrosis (Y) was calculated by the total fibrotic scores (X) according to the experiential formula: Y = X/2 -2; receiver operating curves (ROC) showed that the best cut-off values for differentiating cirrhosis from chronic hepatitis was 10 with a sensitivity of 87.8% and a specificity of 97.6%.

CONCLUSIONS:

The total fibrotic scores of ultrasonic dimensional image provide a semiquantitative marker to evaluate liver fibrosis and differentiate cirrhosis from chronic hepatitis.

PMID:
11721453
[Indexed for MEDLINE]

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