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Resuscitation. 2001 Oct;51(1):97-101.

Thrombolysis with recombinant tissue plasminogen activator during cardiopulmonary resuscitation in fulminant pulmonary embolism. A case series.

Author information

1
Intensive Care Unit, Critical Care and Emergencies Department, Hospital de Poniente, El Ejido, Almeria, Spain. mrb1604@teleline.es

Abstract

OBJECTIVE:

To describe our outcomes using thrombolysis during the cardiopulmonary resuscitation (CPR) of patients in cardiorespiratory arrest (CA) caused by fulminant pulmonary embolism (FPE).

DESIGN:

A case series.

SETTING:

Intensive care units of a district hospital and a referral centre.

PATIENTS:

Six patients that suffered CA secondary to an FPE.

INTERVENTIONS:

Administration of recombinant tissue plasminogen activator during usual CPR manoeuvres when there was a strong suspicion of FPE. Permission for the thrombolytic therapy was sought from family members in all cases.

RESULTS:

Four out of the six patients survived and remain symptom-free. The thrombolysis was not associated with any fatal complications.

CONCLUSIONS:

Early thrombolysis during CPR manoeuvres for CA apparently caused by an FPE may reduce the mortality rate among these patients.

PMID:
11719180
[Indexed for MEDLINE]

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