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Biochim Biophys Acta. 2001 Nov 11;1522(1):53-8.

Molecular cloning of a mouse scavenger receptor with C-type lectin (SRCL)(1), a novel member of the scavenger receptor family.

Author information

1
Division of Molecular Regenerative Medicine, Course of Advanced Medicine, Osaka Graduate School of Medicine, Japan. nakamura@onbich.med.osaka-u.ac.jp

Abstract

The cDNA clone encoding a mouse scavenger receptor with C-type lectin (SRCL), a novel member of the scavenger receptor family, has been isolated from a mouse embryonic cDNA library. The predicted cDNA sequence contains a 2226 bp open reading frame encoding a coiled-coil, collagen-like, C-type lectin/carbohydrate recognition domain with an overall sequence identity of 92% to human SRCL. In contrast to human, mouse SRCL mRNA was expressed ubiquitously in various adult tissues including the liver and spleen, in which human SRCL mRNA was under detection limits. Mouse SRCL mRNA was expressed in the macrophage cell line J774A.1 cells at a high level and in the embryo as early as E9.

PMID:
11718900
DOI:
10.1016/s0167-4781(01)00284-6
[Indexed for MEDLINE]

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