Abstract
A trivalent (feline panleucopenia, feline herpesvirus, feline calicivirus), modified live, commercially available cat vaccine was used at either 6, 9 and 12 weeks of age (early schedule) or 9 and 12 weeks of age (conventional schedule), and the serological response to vaccination was assessed. The level of maternally derived antibody present at 6 weeks of age was also established. The use of early vaccination at 6 weeks of age induced an antibody response to each virus by 9 weeks of age in a significant proportion of kittens compared with unvaccinated littermates. There was no difference between the conventionally and early-vaccinated groups in terms of antibody response to any antigen by 12 and 15 weeks of age.
Copyright 2001 European Society of Feline Medicine.
Publication types
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Clinical Trial
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Multicenter Study
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Age Factors
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Animals
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Antibodies, Viral / biosynthesis
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Antibodies, Viral / blood
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Caliciviridae Infections / prevention & control
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Caliciviridae Infections / veterinary
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Calicivirus, Feline / immunology*
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Cat Diseases / immunology
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Cat Diseases / prevention & control*
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Cat Diseases / virology
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Cats
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Feline Panleukopenia / prevention & control
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Feline Panleukopenia Virus / immunology*
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Herpesviridae Infections / prevention & control
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Herpesviridae Infections / veterinary
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Immunity, Maternally-Acquired
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Treatment Outcome
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Vaccination / veterinary
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Varicellovirus / immunology*
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Viral Vaccines / administration & dosage
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Viral Vaccines / immunology*
Substances
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Antibodies, Viral
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Viral Vaccines