A field trial to assess the effect of vaccination against feline herpesvirus, feline calicivirus and feline panleucopenia virus in 6-week-old kittens

J Feline Med Surg. 2001 Mar;3(1):17-22. doi: 10.1053/jfms.2000.0154.

Abstract

A trivalent (feline panleucopenia, feline herpesvirus, feline calicivirus), modified live, commercially available cat vaccine was used at either 6, 9 and 12 weeks of age (early schedule) or 9 and 12 weeks of age (conventional schedule), and the serological response to vaccination was assessed. The level of maternally derived antibody present at 6 weeks of age was also established. The use of early vaccination at 6 weeks of age induced an antibody response to each virus by 9 weeks of age in a significant proportion of kittens compared with unvaccinated littermates. There was no difference between the conventionally and early-vaccinated groups in terms of antibody response to any antigen by 12 and 15 weeks of age.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Animals
  • Antibodies, Viral / biosynthesis
  • Antibodies, Viral / blood
  • Caliciviridae Infections / prevention & control
  • Caliciviridae Infections / veterinary
  • Calicivirus, Feline / immunology*
  • Cat Diseases / immunology
  • Cat Diseases / prevention & control*
  • Cat Diseases / virology
  • Cats
  • Feline Panleukopenia / prevention & control
  • Feline Panleukopenia Virus / immunology*
  • Herpesviridae Infections / prevention & control
  • Herpesviridae Infections / veterinary
  • Immunity, Maternally-Acquired
  • Treatment Outcome
  • Vaccination / veterinary
  • Varicellovirus / immunology*
  • Viral Vaccines / administration & dosage
  • Viral Vaccines / immunology*

Substances

  • Antibodies, Viral
  • Viral Vaccines