[Pathology of liver cirrhosis and portal hypertension]

Radiologe. 2001 Oct;41(10):833-9. doi: 10.1007/s001170170054.
[Article in German]

Abstract

Cirrhosis is a late stage finding in chronic liver diseases of different aetiology. It is defined morphologically as a diffuse process with the presence of fibrosis and structurally abnormal nodules. The consequences of cirrhosis are both, mechanical and functional. The mechanical complications result from intra- and extrahepatic shunting of blood and portal hypertension while the functional relevance bases upon a failure of liver cells to perform their physiological role in metabolism, synthesis and secretion. Beside these complications that are directly linked to liver function cirrhosis in itself is a risk factor for hepatocellular carcinoma.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Carcinoma, Hepatocellular / pathology
  • Cell Transformation, Neoplastic / pathology
  • Humans
  • Hypertension, Portal / etiology
  • Hypertension, Portal / pathology*
  • Liver / pathology
  • Liver Cirrhosis / etiology
  • Liver Cirrhosis / pathology*
  • Liver Neoplasms / pathology