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J Am Acad Dermatol. 2001 Dec;45(6):914-8.

Regression of multifocal, skin-restricted, CD30-positive large T-cell lymphoma with interferon alfa and bexarotene therapy.

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1
Department of Dermatology, University of Pennsylvania, Philadelphia, USA. french@cmu.unige.ch

Abstract

We report the case of a 43-year-old male patient with persistent multifocal, skin-restricted, CD30-positive, large T-cell lymphoma. Combination therapy of systemic interferon alfa and oral bexarotene was initiated on an experimental basis in the hope of circumventing therapies such as methotrexate, radiotherapy, or multiple-agent chemotherapy that may be required in such cases. This treatment was associated with rapid and marked regression of the patient's cutaneous lesions.

PMID:
11712039
DOI:
10.1067/mjd.2001.117519
[Indexed for MEDLINE]
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