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Humangenetik. 1975 May 26;28(1):39-42.

Evidence for two active X chromosomes in a human XXY triploid.


A human XXY chromatin negative triploid culture has been found to have both the A and B isozymes of glucose-6-phosphate dehydrogenase, as well as an intermediately migrating AB (hybrid) band. This finding indicates that the cells in this culture each possess 2 active X chromosomes. Possible mechanisms producing the abnormalities seen in this disorder are presented and discussed.

[Indexed for MEDLINE]

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