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Zentralbl Gynakol. 2001 Sep;123(9):529-33.

[Effect of Urapidil in antihypertensive therapy of preeclampsia on newborns].

[Article in German]

Author information

1
Universit├Ąts-Frauenklinik, Heidelberg. michael_schulz@med.uni-heidelberg.de

Abstract

OBJECTIVE:

For the therapy of preeclamptic patients is Urapidil besides Dihydralazine another possible option for iv-therapy with good results in first clinical studies. Effects of both drugs on the newborns were observed. -

METHODS:

The maternal and fetal Urapidil plasma-concentrations and cardiovascular parameters of the newborns were observed in a randomised comparative therapy-study. -

RESULTS:

We found low fetal Urapidil plasma-concentrations as well as a less influence on cardiovascular parameters compared to dihydralazine. -

DISCUSSION:

With Urapaidil we have another therapeutic option in preeclampsia where we could not show any negative side-effects on the newborns.

PMID:
11709746
DOI:
10.1055/s-2001-18226
[Indexed for MEDLINE]

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