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Microbes Infect. 2001 Nov;3(13):1157-66.

Microbiological and immunological strategies for treatment of inflammatory bowel disease.

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Department of Molecular Biology, Flanders Interuniversity Institute for Biotechnology and Ghent University, KL. Ledeganckstraat 35, B-9000, Gent, Belgium.


Chronic inflammatory bowel diseases such as Crohn's disease or ulcerative colitis, affect around 1 in every 1000 individuals in western countries. They probably result from an inappropriate reaction towards the commensal microflora and are currently treated with anti-inflammatory drugs or surgery. Novel strategies aim at blocking lymphocyte recruitment and activation, improved targeting of therapeutics and modification of gut microflora.

[Indexed for MEDLINE]

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