Format

Send to

Choose Destination
FEBS Lett. 2001 Nov 9;508(1):143-8.

In silico screening for tumour-specific expressed sequences in human genome.

Author information

1
Vavilov Institute of General Genetics, 3 Gubkina Str., Moscow 119991, Russia. baranova@vigg.ru

Abstract

A computer-based differential display tool named HsAnalyst has been developed and successfully used for the comparison of expression patterns in a set of tumours versus a set of normal tissues. A list of EST clusters highly represented in tumours and rarely observed in normal tissues has been developed as a resulting output file of the program. These differentially expressed EST clusters (genes) can be useful for developing new tumour markers and prognostic indicators for a wide set of human malignancies. Tumour-specific protein-coding genes may be considered a manifestation of tumour-specific gene expression.

PMID:
11707285
DOI:
10.1016/s0014-5793(01)03028-9
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center