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Curr Opin Cell Biol. 2001 Dec;13(6):754-61.

Chromosome cohesion and segregation in mitosis and meiosis.

Author information

1
Chromosome Segregation Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, London WC2A 3PX, UK. f.uhlmann@icrf.icnet.uk

Abstract

The faithful segregation of the genetic material into daughter cells during cell division is crucial for the production of healthy progeny. Sister chromatid cohesion and separation are fundamental to this process. Progress has been made in our molecular understanding of cohesion and mechanisms for the dissolution of cohesion have been uncovered.

PMID:
11698193
DOI:
10.1016/s0955-0674(00)00279-9
[Indexed for MEDLINE]

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