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Fetal Diagn Ther. 2001 Nov-Dec;16(6):402-6.

In utero evaluation and the long-term prognosis of living infants with cystic hygroma.

Author information

  • 1Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Abstract

OBJECTIVE:

The aim is to evaluate the natural course and the long-term prognosis of cystic hygroma following live birth.

METHODS:

Of 39 cases, 12 were excluded because of either artificial termination or intrauterine treatment. 27 cases were retrospectively classified into 2 groups based on the outcome, and the clinical profiles were compared. The long-term prognosis was analyzed for live births.

RESULTS:

5 (18.5%) and 22 (81.5%) cases resulted in live birth and fetal demise, respectively. Both the frequency of hydrops fetalis and the maximum size of the cyst were more significantly associated with a poor prognosis (p < 0.01). Of 5 live births, 3 cases with chromosomal or structural abnormalities were handicapped.

CONCLUSIONS:

Hydrops fetalis and cyst size are poor prognostic factors, and fetal chromosome and structural malformations should be taken into account when predicting the long-term prognosis.

PMID:
11694746
DOI:
53948
[PubMed - indexed for MEDLINE]
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