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Gastrointest Endosc Clin N Am. 2001 Oct;11(4):659-82, vi-vii.

Polyposis syndromes: pediatric implications.

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1
Department of Pediatrics, St Mark's Hospital, Harrow, Middx, United Kingdom. warrenhyer@aol.com

Abstract

The diagnosis of a polyposis syndrome, such as juvenile polyposis, Peutz-Jeghers syndrome, and familial adenomatous polyposis, requires knowledge of the site, number, and histologic type of the polyps and an appreciation of relevant family history. Children and adolescents with polyposis syndromes are faced with not only the immediate complications of the polyps, such as intussusception or bleeding, but also the extraintestinal manifestations and the long-term risk for malignancy. This article reviews the diagnosis, clinical management, surveillance, and surgical options for children with polyposis syndromes and discusses genetics and appropriate screening programs.

PMID:
11689361
[Indexed for MEDLINE]
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