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Clin Diagn Lab Immunol. 2001 Nov;8(6):1271-6.

Analogs of Eap protein are conserved and prevalent in clinical Staphylococcus aureus isolates.

Author information

1
Institute of Medical Microbiology, University of Muenster, Muenster, Germany. muzaffa@uni-muenster.de

Abstract

Map and Eap are secreted Staphylococcus aureus proteins that interact with various extracellular matrix molecules. PCR analysis using map primers yielded positive reactions in 97.9% of S. aureus isolates but not in Staphylococcus epidermidis isolates. Cloning and sequencing of the conferring genes revealed a high degree of overall homology combined with size variability of the gene product due to various repeat numbers and early translation termination in a poly(A) region. Thus, Map and Eap may provide a potential novel tool for S. aureus identification and typing.

PMID:
11687475
PMCID:
PMC96261
DOI:
10.1128/CDLI.8.6.1271-1276.2001
[Indexed for MEDLINE]
Free PMC Article

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