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Cornea. 2001 Nov;20(8):807-10.

Treatment of superior limbic keratoconjunctivitis by application of autologous serum.

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Department of Ophthalmology, Tokyo Dental College, Ichikawa City, Chiba, Japan.



To determine the efficacy of autologous serum drops in the treatment of superior limbic keratoconjunctivitis (SLK).


Twenty-two eyes of 11 patients were diagnosed with SLK. All eyes were treated with 20% diluted autologous serum eyedrops 10 times a day in addition to ongoing treatment of dry eye. Fluorescein and rose bengal staining scores, as well as subjective symptom gradings, were performed before and after 4 weeks of therapy.


Nine of the 11 patients responded well to treatment (82%). The average rose bengal and fluorescein score improved ( p < 0.05), and there was subjective improvement.


Autologous serum application can be used as an alternative mode of therapy in SLK.

[Indexed for MEDLINE]

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