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Mol Cell. 2001 Oct;8(4):734-6.

A step backward in advancing DNA replication: rescue of stalled replication forks by RecG.

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Section of Microbiology, University of California at Davis, Davis, CA 95616, USA.


In the October 5 issue of Cell, Singleton et al. report the crystal structure of RecG protein bound to an analog of a stalled DNA replication fork. This structure shows how RecG can recognize branched DNA structures and suggests a mechanism for fork reversal, an early event in recombination-dependent reinitiation of DNA replication.

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