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Neurology. 2001 Oct 23;57(8):1488-91.

Fish oil supplementation improves visual evoked potentials in children with phenylketonuria.

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  • 1Division of Metabolic Diseases and Nutrition, Dr. von Haunersches Kinderspital, Munich, Germany.

Abstract

Visual evoked potentials (VEP) were measured in 36 patients with early-treated phenylketonuria (PKU; aged 1 to 11 years) and good metabolic control before and after supplementation with omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) from fish oil. Patients with PKU had significantly longer P100 latencies than 22 age-matched control subjects. After 3 months of LC-PUFA supplementation, VEP latencies improved significantly in PKU patients but did not change in 12 untreated healthy children. The authors conclude that omega-3 LC-PUFA are essential substrates for nervous system function even beyond infancy.

PMID:
11673596
[PubMed - indexed for MEDLINE]
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